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Crystal structure of human IRAK1

Interleukin 1 (IL-1) receptor-associated kinases (IRAKs) are serine/threonine kinases that play critical roles in initiating innate immune responses against foreign pathogens and other types of dangers through their role in Toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) mediated signali...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Li, Qiao, Qi, Ferrao, Ryan, Shen, Chen, Hatcher, John M., Buhrlage, Sara J., Gray, Nathanael S., Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754798/
https://ncbi.nlm.nih.gov/pubmed/29208712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714386114
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