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Structural insights into how GTP-dependent conformational changes in a metallochaperone UreG facilitate urease maturation

The ability of metallochaperones to allosterically regulate the binding/release of metal ions and to switch protein-binding partners along the metal delivery pathway is essential to the metallation of the metalloenzymes. Urease, catalyzing the hydrolysis of urea into ammonia and carbon dioxide, cont...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yuen, Man Hon, Fong, Yu Hang, Nim, Yap Shing, Lau, Pak Ho, Wong, Kam-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754787/
https://ncbi.nlm.nih.gov/pubmed/29203664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712658114
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