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Additive Phenotypes Underlie Epistasis of Fitness Effects

Gene interactions, or epistasis, play a large role in determining evolutionary outcomes. The ruggedness of fitness landscapes, and thus the predictability of evolution and the accessibility of high-fitness genotypes, is determined largely by the pervasiveness of epistasis and the degree of correlati...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Sackman, Andrew M., Rokyta, Darin R.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753867/
https://ncbi.nlm.nih.gov/pubmed/29113978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300451
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