The microRNA miR-31 inhibits CD8(+) T cell function in chronic viral infection

During infection, antigen-specific T cells undergo tightly regulated developmental transitions controlled by transcriptional and post-transcriptional regulation of gene expression. We found that the microRNA miR-31 was strongly induced by activation of the T cell antigen receptor (TCR) in a pathway...

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Bibliografske podrobnosti
izdano v:Nat Immunol
Main Authors: Moffett, Howell F, Cartwright, Adam N R, Kim, Hye-Jung, Godec, Jernej, Pyrdol, Jason, Äijö, Tarmo, Martinez, Gustavo J, Rao, Anjana, Lu, Jun, Golub, Todd R, Cantor, Harvey, Sharpe, Arlene H, Novina, Carl D, Wucherpfennig, Kai W
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753758/
https://ncbi.nlm.nih.gov/pubmed/28530712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3755
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