MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

Identification and treatment of abdominal aortic aneurysm (AAA) remains among the most prominent challenges in vascular medicine. MicroRNAs are crucial regulators of cardiovascular pathology and represent possible targets for the inhibition of AAA expansion. We identified microRNA-21 (miR-21) as a k...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Maegdefessel, Lars, Azuma, Junya, Toh, Ryuji, Deng, Alicia, Merk, Denis R., Raiesdana, Azad, Leeper, Nicholas J., Raaz, Uwe, Schoelmerich, Anke M., McConnell, Michael V., Dalman, Ronald L., Spin, Joshua M., Tsao, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753594/
https://ncbi.nlm.nih.gov/pubmed/22357537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003441
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