Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development

MicroRNAs (miRs) regulate gene expression at the posttranscriptional level and play crucial roles in vascular integrity. As such, they may have a role in modifying abdominal aortic aneurysm (AAA) expansion, the pathophysiological mechanisms of which remain incompletely explored. Here, we investigate...

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Detalhes bibliográficos
Main Authors: Maegdefessel, Lars, Azuma, Junya, Toh, Ryuji, Merk, Denis R., Deng, Alicia, Chin, Jocelyn T., Raaz, Uwe, Schoelmerich, Anke M., Raiesdana, Azad, Leeper, Nicholas J., McConnell, Michael V., Dalman, Ronald L., Spin, Joshua M., Tsao, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266800/
https://ncbi.nlm.nih.gov/pubmed/22269326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61598
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