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Assessment of usnic acid toxicity in rat primary hepatocytes using (13)C isotopomer distribution analysis of lactate, glutamate and glucose
The lichen metabolite usnic acid (UA) has been promoted as a dietary supplement for weight loss, although cases of hepatotoxicity have been reported. Here we evaluated UA-associated hepatotoxicity in vitro using isolated rat hepatocytes. We measured cell viability and ATP content to evaluate UA indu...
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| Publicado en: | Food Chem Toxicol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5753584/ https://ncbi.nlm.nih.gov/pubmed/21802472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2011.07.047 |
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