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HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates (13)C Isotopomer Data

The liver performs many essential metabolic functions, which can be studied using computational models of hepatocytes. Here we present HepatoDyn, a highly detailed dynamic model of hepatocyte metabolism. HepatoDyn includes a large metabolic network, highly detailed kinetic laws, and is capable of dy...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Foguet, Carles, Marin, Silvia, Selivanov, Vitaly A., Fanchon, Eric, Lee, Wai-Nang Paul, Guinovart, Joan J., de Atauri, Pedro, Cascante, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849781/
https://ncbi.nlm.nih.gov/pubmed/27124774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004899
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