Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico

HIV circumvents HLA class I-restricted CD8(+) T-cell responses through selection of escape mutations that leave characteristic mutational “footprints,” also known as HLA-associated polymorphisms (HAPs), on HIV sequences at the population level. While many HLA footprints are universal across HIV subt...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Soto-Nava, Maribel, Avila-Ríos, Santiago, Valenzuela-Ponce, Humberto, García-Morales, Claudia, Carlson, Jonathan M., Tapia-Trejo, Daniela, Garrido-Rodriguez, Daniela, Alva-Hernández, Selma N., García-Tellez, Thalía A., Murakami-Ogasawara, Akio, Mallal, Simon A., John, Mina, Brockman, Mark A., Brumme, Chanson J., Brumme, Zabrina L., Reyes-Teran, Gustavo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Genetic Diversity and Evolution
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752930/
https://ncbi.nlm.nih.gov/pubmed/29093100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01128-17
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