Cathepsin D protects renal tubular cells from damage induced by high glucose independent of its enzymatic activity

Although glomerular and vascular damage have been considered the main characteristics of diabetic kidney disease (DKD), accumulating data now indicate that tubular atrophy also plays a major role. Cathepsin D (CatD) is the major aspartate protease within lysosomes. The current study demonstrated tha...

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Udgivet i:Am J Transl Res
Main Authors: Du, Feng, Wang, Tian, Li, Si, Meng, Xin, Zhang, Hai-Yan, Li, De-Tian, Du, Zhen-Xian, Wang, Hua-Qin
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752902/
https://ncbi.nlm.nih.gov/pubmed/29312504
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