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Cathepsin D protects renal tubular cells from damage induced by high glucose independent of its enzymatic activity

Although glomerular and vascular damage have been considered the main characteristics of diabetic kidney disease (DKD), accumulating data now indicate that tubular atrophy also plays a major role. Cathepsin D (CatD) is the major aspartate protease within lysosomes. The current study demonstrated tha...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Du, Feng, Wang, Tian, Li, Si, Meng, Xin, Zhang, Hai-Yan, Li, De-Tian, Du, Zhen-Xian, Wang, Hua-Qin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752902/
https://ncbi.nlm.nih.gov/pubmed/29312504
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