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Targeting of CD122 enhances antitumor immunity by altering the tumor immune environment
Mounting evidence demonstrates that CD8(+)CD122(+) T cells have suppressive properties with the capacity to inhibit T cell responses. Therefore, these cells are rational targets for cancer immunotherapy. Here, we demonstrate that CD122 monoclonal antibody (mAb; aCD122) therapy significantly suppress...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752510/ https://ncbi.nlm.nih.gov/pubmed/29312597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22642 |
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