Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy

IgA nephropathy (IgAN) is characterized by high serum IgA levels and IgA deposition in the renal mesangium. Recent research has indicated that pathogenic IgA may originate from affected tonsils, where present enhancement of IgA production by IgA class switching and immuno-activation. Tripterygium Wi...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Li, Huining, Kong, Dan, Xu, Yangyang, Li, Xiaomei, Yao, Guodong, Chen, Kexin, You, Qi, Shi, Qingtao, Zhang, Lei, Wang, Xin, Yuan, Dawei, Miao, Shusheng, Geng, Jingshu, Jin, Xiaoming, Meng, Hongxue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752501/
https://ncbi.nlm.nih.gov/pubmed/29312588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22561
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