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Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy

IgA nephropathy (IgAN) is characterized by high serum IgA levels and IgA deposition in the renal mesangium. Recent research has indicated that pathogenic IgA may originate from affected tonsils, where present enhancement of IgA production by IgA class switching and immuno-activation. Tripterygium Wi...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Li, Huining, Kong, Dan, Xu, Yangyang, Li, Xiaomei, Yao, Guodong, Chen, Kexin, You, Qi, Shi, Qingtao, Zhang, Lei, Wang, Xin, Yuan, Dawei, Miao, Shusheng, Geng, Jingshu, Jin, Xiaoming, Meng, Hongxue
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752501/
https://ncbi.nlm.nih.gov/pubmed/29312588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22561
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