Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy

IgA nephropathy (IgAN) is characterized by high serum IgA levels and IgA deposition in the renal mesangium. Recent research has indicated that pathogenic IgA may originate from affected tonsils, where present enhancement of IgA production by IgA class switching and immuno-activation. Tripterygium Wi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Huining, Kong, Dan, Xu, Yangyang, Li, Xiaomei, Yao, Guodong, Chen, Kexin, You, Qi, Shi, Qingtao, Zhang, Lei, Wang, Xin, Yuan, Dawei, Miao, Shusheng, Geng, Jingshu, Jin, Xiaoming, Meng, Hongxue
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752501/
https://ncbi.nlm.nih.gov/pubmed/29312588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22561
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