Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37

We previously identified a novel Rab small GTPase protein, Rab37, which plays a critical role in regulating exocytosis of secreted glycoproteins, tissue inhibitor of metalloproteinases 1 (TIMP1) to suppress lung cancer metastasis. Patients with preserved Rab37 protein expression were associated with...

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Pubblicato in:Oncotarget
Autori principali: Tzeng, Hong-Tai, Li, Tsung-Hsin, Tang, Yen-An, Tsai, Chung-Han, Frank Lu, Pei-Jung, Lai, Wu-Wei, Chiang, Chi-Wu, Wang, Yi-Ching
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752464/
https://ncbi.nlm.nih.gov/pubmed/29312551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20998
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