Regulatory T cells with a defect in inhibition on co-stimulation deteriorated primary biliary cholangitis

Regulatory T cells (Tregs) play an indispensable role in the progression of primary biliary cholangitis (PBC). Although Tregs could normalize costimulation in in vivo and in vitro models, it is obscure whether and how Tregs mediate these effects in PBC. Herein we focused on the quantitative and func...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Chen, Jianing, Hou, Xianliang, Jia, Hongyu, Cui, Guangying, Wu, Zhongwen, Wang, Lin, Lu, Chong, Wu, Wei, Wei, Yingfeng, Uede, Toshimitsu, Li, Lanjuan, Lian, Zhexiong, Diao, Hongyan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper: Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752452/
https://ncbi.nlm.nih.gov/pubmed/29312539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22658
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