Osteopontin promotes dendritic cell maturation and function in response to HBV antigens

PURPOSE: Dendritic cells (DCs) play critical roles in promoting innate and adaptive immunity in microbial infection. Functional impairment of DCs may mediate the suppression of viral-specific T-cell immune response in chronic hepatitis B (CHB) patients. Osteopontin (OPN) is involved in several liver...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Cui, Guangying, Chen, Jianing, He, Jianqin, Lu, Chong, Wei, Yingfeng, Wang, Lin, Xu, Xuejun, Li, Lanjuan, Uede, Toshimitsu, Diao, Hongyan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472071/
https://ncbi.nlm.nih.gov/pubmed/26109844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S81656
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