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Dengue vaccine–induced CD8(+) T cell immunity confers protection in the context of enhancing, interfering maternal antibodies

Declining levels of maternal antibodies were shown to sensitize infants born to dengue-immune mothers to severe disease during primary infection, through the process of antibody-dependent enhancement of infection (ADE). With the recent approval for human use of Sanofi-Pasteur’s chimeric dengue vacci...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lam, Jian Hang, Chua, Yen Leong, Lee, Pei Xuan, Martínez Gómez, Julia María, Ooi, Eng Eong, Alonso, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752305/
https://ncbi.nlm.nih.gov/pubmed/29263304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94500
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