Mutational profiles of breast cancer metastases from a rapid autopsy series reveal multiple evolutionary trajectories

Heterogeneity within and among tumors in a metastatic cancer patient is a well-established phenomenon that may confound treatment and accurate prognosis. Here, we used whole-exome sequencing to survey metastatic breast cancer tumors from 5 patients in a rapid autopsy program to construct the origin...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Avigdor, Bracha Erlanger, Cimino-Mathews, Ashley, DeMarzo, Angelo M., Hicks, Jessica L., Shin, James, Sukumar, Saraswati, Fetting, John, Argani, Pedram, Park, Ben H., Wheelan, Sarah J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752302/
https://ncbi.nlm.nih.gov/pubmed/29263308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96896
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