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Mutational profiles of breast cancer metastases from a rapid autopsy series reveal multiple evolutionary trajectories
Heterogeneity within and among tumors in a metastatic cancer patient is a well-established phenomenon that may confound treatment and accurate prognosis. Here, we used whole-exome sequencing to survey metastatic breast cancer tumors from 5 patients in a rapid autopsy program to construct the origin...
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| Udgivet i: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752302/ https://ncbi.nlm.nih.gov/pubmed/29263308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96896 |
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