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Human pericytes adopt myofibroblast properties in the microenvironment of the IPF lung

Idiopathic pulmonary fibrosis (IPF) is a fatal disease of unknown etiology characterized by a compositionally and mechanically altered extracellular matrix. Poor understanding of the origin of α-smooth muscle actin (α-SMA) expressing myofibroblasts has hindered curative therapies. Though proposed as...

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Vydáno v:JCI Insight
Hlavní autoři: Sava, Parid, Ramanathan, Anand, Dobronyi, Amelia, Peng, Xueyan, Sun, Huanxing, Ledesma-Mendoza, Adrian, Herzog, Erica L., Gonzalez, Anjelica L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752282/
https://ncbi.nlm.nih.gov/pubmed/29263297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96352
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