A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression

Although genome-wide association studies have shown that potassium voltage-gated channel subfamily Q member 1 (KCNQ1) is one of the genes that is most significantly associated with type 2 diabetes mellitus (T2DM), functionally annotating disease-associated single nucleotide polymorphisms (SNPs) rema...

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Publicado no:Int J Mol Med
Main Authors: Hiramoto, Masaki, Udagawa, Haruhide, Ishibashi, Naoko, Takahashi, Eri, Kaburagi, Yasushi, Miyazawa, Keisuke, Funahashi, Nobuaki, Nammo, Takao, Yasuda, Kazuki
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752166/
https://ncbi.nlm.nih.gov/pubmed/29207083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3273
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