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Evolution of the CDKN1C-KCNQ1 imprinted domain

BACKGROUND: Genomic imprinting occurs in both marsupial and eutherian mammals. The CDKN1C and IGF2 genes are both imprinted and syntenic in the mouse and human, but in marsupials only IGF2 is imprinted. This study examines the evolution of features that, in eutherians, regulate CDKN1C imprinting. RE...

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Bibliographic Details
Main Authors: Ager, Eleanor I, Pask, Andrew J, Gehring, Helen M, Shaw, Geoff, Renfree, Marilyn B
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427030/
https://ncbi.nlm.nih.gov/pubmed/18510768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-163
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