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A circuit-based mechanism underlying familiarity signaling and the preference for novelty

Novelty preference (NP) is an evolutionarily conserved, essential survival mechanism often dysregulated in neuropsychiatric disorders. NP is mediated by a motivational dopamine signal that increases in response to novel stimuli thereby driving exploration. However, the mechanism by which once novel...

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Detalles Bibliográficos
Publicado en:Nat Neurosci
Main Authors: Molas, Susanna, Zhao-Shea, Rubing, Liu, Liwang, DeGroot, Steven R., Gardner, Paul D., Tapper, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752132/
https://ncbi.nlm.nih.gov/pubmed/28714952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4607
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