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Genomic Form of Rhodopsin DNA Nanoparticles Rescued Autosomal Dominant Retinitis Pigmentosa in the P23H Knock-in Mouse Model
Retinitis pigmentosa (RP) is a group of inherited retinal degenerative conditions and a leading cause of irreversible blindness. 25%–30% of RP cases are caused by inherited autosomal dominant (ad) mutations in the rhodopsin (Rho) protein of the retina, which impose a barrier for developing therapeut...
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| Pubblicato in: | Biomaterials |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752119/ https://ncbi.nlm.nih.gov/pubmed/29232624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.12.004 |
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