Comparison of microbial DNA enrichment tools for metagenomic whole genome sequencing()

Metagenomic whole genome sequencing for detection of pathogens in clinical samples is an exciting new area for discovery and clinical testing. A major barrier to this approach is the overwhelming ratio of human to pathogen DNA in samples with low pathogen abundance, which is typical of most clinical...

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Pubblicato in:J Microbiol Methods
Autori principali: Thoendel, Matthew, Jeraldo, Patricio R., Greenwood-Quaintance, Kerryl E., Yao, Janet Z., Chia, Nicholas, Hanssen, Arlen D., Abdel, Matthew P., Patel, Robin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752108/
https://ncbi.nlm.nih.gov/pubmed/27237775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mimet.2016.05.022
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