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Challenges of Integrating Stochastic Dynamics and Cryo-electron Tomograms in Whole-cell Simulations

Cryo-electron tomography (cryo-ET) has rapidly emerged as a powerful tool to investigate the internal, three-dimensional spatial organization of the cell. In parallel, the GPU-based technology to perform spatially resolved stochastic simulations of whole cells has arisen, allowing the simulation of...

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Bibliografiske detaljer
Udgivet i:J Phys Chem B
Main Authors: Earnest, Tyler M., Watanabe, Reika, Stone, John E., Mahamid, Julia, Baumeister, Wolfgang, Villa, Elizabeth, Luthey-Schulten, Zaida
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751760/
https://ncbi.nlm.nih.gov/pubmed/28291359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b00672
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