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Substantia Nigra Volume Loss Before Basal Forebrain Degeneration in Early Parkinson Disease

OBJECTIVE: To test the hypothesis that degeneration of the substantia nigra pars compacta (SNc) precedes that of the cholinergic basal forebrain (BF) in Parkinson disease (PD) using new multispectral structural magnetic resonance (MR) imaging tools to measure the volumes of the SNc and BF. DESIGN: M...

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書誌詳細
出版年:JAMA Neurol
主要な著者: Ziegler, David A., Wonderlick, Julien S., Ashourian, Paymon, Hansen, Leslie A., Young, Jeremy C., Murphy, Alex J., Koppuzha, Cecily K., Growdon, John H., Corkin, Suzanne
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751707/
https://ncbi.nlm.nih.gov/pubmed/23183921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.597
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