Lipopolysaccharide-Induced Acute Kidney Injury Is Dependent on an IL-18 Receptor Signaling Pathway

The proinflammatory cytokine interleukin (IL)-18 is an important mediator of the organ failure induced by endotoxemia. IL-18 (known as an interferon-gamma (IFN-γ) inducing factor), and other inflammatory cytokines have important roles in lipopolysaccharide (LPS)-induced acute kidney injury (AKI). We...

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Publicado no:Int J Mol Sci
Main Authors: Nozaki, Yuji, Hino, Shoichi, Ri, Jinhai, Sakai, Kenji, Nagare, Yasuaki, Kawanishi, Mai, Niki, Kaoru, Funauchi, Masanori, Matsumura, Itaru
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751375/
https://ncbi.nlm.nih.gov/pubmed/29261164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122777
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