Foxp3-Positive Regulatory T Cells Contribute to Antifibrotic Effects in Renal Fibrosis via an Interleukin-18 Receptor Signaling Pathway

Renal interstitial fibrosis is a common lesion in the process of various progressive renal diseases. Interleukin (IL)-18 is a proinflammatory cytokine that plays an important role in the induction of Th1 responses and is associated with renal interstitial fibrosis, but the mechanism of fibrosis rema...

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Bibliografiske detaljer
Udgivet i:Front Med (Lausanne)
Main Authors: Hirooka, Yasuaki, Nozaki, Yuji, Niki, Kaoru, Inoue, Asuka, Sugiyama, Masafumi, Kinoshita, Koji, Funauchi, Masanori, Matsumura, Itaru
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738332/
https://ncbi.nlm.nih.gov/pubmed/33344483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2020.604656
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