The Early Dendritic Cell Signaling Induced by Virulent Francisella tularensis Strain Occurs in Phases and Involves the Activation of Extracellular Signal-Regulated Kinases (ERKs) and p38 In the Later Stage

Dendritic cells (DCs) infected by Francisella tularensis are poorly activated and do not undergo classical maturation process. Although reasons of such unresponsiveness are not fully understood, their impact on the priming of immunity is well appreciated. Previous attempts to explain the behavior of...

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Publicat a:Mol Cell Proteomics
Autors principals: Fabrik, Ivo, Link, Marek, Putzova, Daniela, Plzakova, Lenka, Lubovska, Zuzana, Philimonenko, Vlada, Pavkova, Ivona, Rehulka, Pavel, Krocova, Zuzana, Hozak, Pavel, Santic, Marina, Stulik, Jiri
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750852/
https://ncbi.nlm.nih.gov/pubmed/29046388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000160
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