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The Early Dendritic Cell Signaling Induced by Virulent Francisella tularensis Strain Occurs in Phases and Involves the Activation of Extracellular Signal-Regulated Kinases (ERKs) and p38 In the Later Stage

Dendritic cells (DCs) infected by Francisella tularensis are poorly activated and do not undergo classical maturation process. Although reasons of such unresponsiveness are not fully understood, their impact on the priming of immunity is well appreciated. Previous attempts to explain the behavior of...

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Publicado en:Mol Cell Proteomics
Autores principales: Fabrik, Ivo, Link, Marek, Putzova, Daniela, Plzakova, Lenka, Lubovska, Zuzana, Philimonenko, Vlada, Pavkova, Ivona, Rehulka, Pavel, Krocova, Zuzana, Hozak, Pavel, Santic, Marina, Stulik, Jiri
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750852/
https://ncbi.nlm.nih.gov/pubmed/29046388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000160
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