Dual modulation of human hepatic zonation via canonical and non-canonical Wnt pathways

The hepatic lobule is divided into three zones along the portal-central vein axis. Hepatocytes within each zone exhibit a distinctive gene expression profile that coordinates their metabolic compartmentalization. The zone-dependent heterogeneity of hepatocytes has been hypothesized to result from th...

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Publicado en:Exp Mol Med
Autores principales: McEnerney, Laura, Duncan, Kara, Bang, Bo-Ram, Elmasry, Sandra, Li, Meng, Miki, Toshio, Ramakrishnan, Sadeesh K, Shah, Yatrik M, Saito, Takeshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750478/
https://ncbi.nlm.nih.gov/pubmed/29244788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.226
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