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IL-11 promotes the treatment efficacy of hematopoietic stem cell transplant therapy in aplastic anemia model mice through a NF-κB/microRNA-204/thrombopoietin regulatory axis

Hematopoietic stem cell (HSC) transplantation could be of therapeutic value for aplastic anemia (AA) patients, and immunosuppressants may facilitate the efficiency of the procedure. As anti-inflammatory cytokine interleukin-11 (IL-11) has a thrombopoietic effect, its use in cases of chronic bone mar...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Wang, Yan, Niu, Zhi-yun, Guo, Yu-jie, Wang, Li-hua, Lin, Feng-ru, Zhang, Jing-yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750475/
https://ncbi.nlm.nih.gov/pubmed/29217821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.217
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