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Lysophosphatidic acid protects against acetaminophen-induced acute liver injury

We investigated the effect of lysophosphatidic acid (LPA) in experimental acetaminophen (APAP)-induced acute liver injury. LPA administration significantly reduced APAP-challenged acute liver injury, showing attenuated liver damage, liver cell death and aspartate aminotransferase and alanine aminotr...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Bae, Geon Ho, Lee, Sung Kyun, Kim, Hyung Sik, Lee, Mingyu, Lee, Ha Young, Bae, Yoe-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750472/
https://ncbi.nlm.nih.gov/pubmed/29217823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.203
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