O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia into yeast cells, a step critical for invasion and replicati...

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Udgivet i:mBio
Main Authors: Garfoot, Andrew L., Goughenour, Kristie D., Wüthrich, Marcel, Rajaram, Murugesan V. S., Schlesinger, Larry S., Klein, Bruce S., Rappleye, Chad A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750402/
https://ncbi.nlm.nih.gov/pubmed/29295913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02121-17
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