O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia into yeast cells, a step critical for invasion and replicati...

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Pubblicato in:mBio
Autori principali: Garfoot, Andrew L., Goughenour, Kristie D., Wüthrich, Marcel, Rajaram, Murugesan V. S., Schlesinger, Larry S., Klein, Bruce S., Rappleye, Chad A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750402/
https://ncbi.nlm.nih.gov/pubmed/29295913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02121-17
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