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Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice
Nociceptors rely on cap-dependent translation to rapidly induce protein synthesis in response to pro-inflammatory signals. Comparatively little is known regarding the role of the regulatory factors bound to the 3′ end of mRNA in nociceptor sensitization. Poly(A)-binding protein (PABP) stimulates tra...
Tallennettuna:
| Julkaisussa: | Nat Commun |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5750225/ https://ncbi.nlm.nih.gov/pubmed/29295980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02449-5 |
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