A carregar...

Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice

Nociceptors rely on cap-dependent translation to rapidly induce protein synthesis in response to pro-inflammatory signals. Comparatively little is known regarding the role of the regulatory factors bound to the 3′ end of mRNA in nociceptor sensitization. Poly(A)-binding protein (PABP) stimulates tra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Barragán-Iglesias, Paulino, Lou, Tzu-Fang, Bhat, Vandita D., Megat, Salim, Burton, Michael D., Price, Theodore J., Campbell, Zachary T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750225/
https://ncbi.nlm.nih.gov/pubmed/29295980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02449-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!