Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

The public health threat posed by a looming ‘post-antibiotic’ era necessitates new approaches to antibiotic discovery. Drug development has typically avoided exploitation of membrane-binding properties, in contrast to nature’s control of biological pathways via modulation of membrane-associated prot...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Blaskovich, Mark A. T., Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G., Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E., Sidjabat, Hanna E., Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R., Beevers, Andrew P. G., Smith, Richard A. G., Roberts, Jason A., Paterson, David L., Cooper, Matthew A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750218/
https://ncbi.nlm.nih.gov/pubmed/29295973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02123-w
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