Pacritinib to inhibit JAK/STAT signaling in refractory metastatic colon and rectal cancer

BACKGROUND: Treatment options for patients with refractory colorectal cancer are limited and typically provide a chance of only modest benefit. The goal of this study was to evaluate the benefit of inhibiting the JAK/STAT inflammatory pathway with single agent pacritinib in patients with metastatic...

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Foilsithe in:J Gastrointest Oncol
Main Authors: Regenbogen, Thomas, Chen, Ling, Trinkaus, Kathryn, Wang-Gillam, Andrea, Tan, Benjamin R., Amin, Manik, Pedersen, Katrina S., Park, Haeseong, Suresh, Rama, Lim, Kian-Huat, Ratchford, Emily, Brown, Amberly, Lockhart, A. Craig
Formáid: Artigo
Teanga:Inglês
Foilsithe: AME Publishing Company 2017
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750170/
https://ncbi.nlm.nih.gov/pubmed/29299358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2017.08.16
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