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ET-35 PACRITINIB: A NOVEL JAK/STAT INHIBITOR WITH TRANSLATIONAL RELEVANCE FOR GBM

Glioblastoma multiforme (GBM) is characterized by an aggressive clinical course, therapeutic resistance, and striking molecular heterogeneity. GBM-derived brain tumor initiating cells (BTICs) closely model this molecular heterogeneity and may have a key role in tumor recurrence and therapeutic resis...

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Detalhes bibliográficos
Main Authors: Luchman, Artee, Aman, Ahmed, Al-Awar, Rima, Weiss, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218132/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.35
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