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Regulation of Kisspeptin Synthesis and Release in the Preoptic/Anterior Hypothalamic Region of Prepubertal Female Rats: Actions of IGF-1 and Alcohol

BACKGROUND: Alcohol (ALC) causes suppressed secretion of prepubertal luteinizing hormone-releasing hormone (LHRH). Insulin-like growth factor-1 (IGF-1) and kisspeptin (Kp) are major regulators of LHRH and are critical for puberty. IGF-1 may be an upstream mediator of Kp in the preoptic area and rost...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Hiney, Jill K., Srivastava, Vinod K., Vaden Anderson, Danielle N., Hartzoge, Nicole L., Dees, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750128/
https://ncbi.nlm.nih.gov/pubmed/29072778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13539
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