Rapamycin Does Not Impede Survival or Induction of Antibody Responses to Primary and Heterosubtypic Influenza Infections in Mice

Impairment of immune defenses can contribute to severe influenza infections. Rapamycin is an immunosuppressive drug often used to prevent transplant rejection and is currently undergoing clinical trials for treating cancers and autoimmune diseases. We investigated whether rapamycin has deleterious e...

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Udgivet i:Viral Immunol
Main Authors: Liepkalns, Justine S., Pandey, Aseem, Hofstetter, Amelia R., Kumar, Amrita, Jones, Enitra N., Cao, Weiping, Liu, Feng, Levine, Min Z., Sambhara, Suryaprakash, Gangappa, Shivaprakash
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749914/
https://ncbi.nlm.nih.gov/pubmed/27447349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2016.0056
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