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Behavioral and biochemical sensitivity to low doses of ketamine: influence of estrous cycle in C57BL/6 mice

RATIONALE: Low-dose ketamine is a rapid-acting antidepressant, to which female rodents are more sensitive as compared to males. However, the mechanism mediating this sex difference in ketamine sensitivity remains elusive. OBJECTIVES: We sought to determine whether male and female mice differ in thei...

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Publicat a:Neuropharmacology
Autors principals: Dossat, Amanda M., Wright, Katherine N., Strong, Caroline E., Kabbaj, Mohamed
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749639/
https://ncbi.nlm.nih.gov/pubmed/29175352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.11.022
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