Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease

Histone protein modifications control fate determination during normal development and dedifferentiation during disease. Here, we set out to determine the extent to which dynamic changes to histones affect the differentiated phenotype of ordinarily quiescent adult glomerular podocytes. To do this, w...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Majumder, Syamantak, Thieme, Karina, Batchu, Sri N., Alghamdi, Tamadher A., Bowskill, Bridgit B., Kabir, M. Golam, Liu, Youan, Advani, Suzanne L., White, Kathryn E., Geldenhuys, Laurette, Tennankore, Karthik K., Poyah, Penelope, Siddiqi, Ferhan S., Advani, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749498/
https://ncbi.nlm.nih.gov/pubmed/29227285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95946
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