EP4 inhibition attenuates the development of diabetic and non-diabetic experimental kidney disease

The therapeutic targeting of prostanoid subtype receptors may slow the development of chronic kidney disease (CKD) through mechanisms that are distinct from those of upstream COX inhibition. Here, employing multiple experimental models of CKD, we studied the effects of inhibition of the EP4 receptor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Thieme, Karina, Majumder, Syamantak, Brijmohan, Angela S., Batchu, Sri N., Bowskill, Bridgit B., Alghamdi, Tamadher A., Advani, Suzanne L., Kabir, M. Golam, Liu, Youan, Advani, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469816/
https://ncbi.nlm.nih.gov/pubmed/28611444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03237-3
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