Application of a pharmacokinetics-pharmacodynamics approach to the free propofol plasma levels during coronary artery bypass grafting surgery with hypothermic cardiopulmonary bypass

OBJECTIVES: The objective of this study was to apply a pharmacokinetics-pharmacodynamics approach to investigate the free propofol plasma levels in patients undergoing coronary artery bypass grafting under hypothermic conditions compared with the off-pump procedure. METHODS: Nineteen patients schedu...

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Publicat a:Clinics (Sao Paulo)
Autors principals: Silva-Filho, Carlos R., Barbosa, Ricardo Antonio G., Silva-Jr, Carlindo V., Malbouisson, Luiz M.S., Carmona, Maria José C., Jorge-Santos, Silvia Regina C.
Format: Artigo
Idioma:Inglês
Publicat: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749432/
https://ncbi.nlm.nih.gov/pubmed/29451620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2018/e178
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