Alterations in the epithelial stem cell compartment could contribute to permanent changes in the mucosa of patients with ulcerative colitis

OBJECTIVE: UC is a chronic inflammatory disease of the colonic mucosa. Growing evidence supports a role for epithelial cell defects in driving pathology. Moreover, long-lasting changes in the epithelial barrier have been reported in quiescent UC. Our aim was to investigate whether epithelial cell de...

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Detalles Bibliográficos
Publicado en:Gut
Autores principales: Dotti, Isabella, Mora-Buch, Rut, Ferrer-Picón, Elena, Planell, Núria, Jung, Peter, Masamunt, M Carme, Leal, Raquel Franco, Martín de Carpi, Javier, Llach, Josep, Ordás, Ingrid, Batlle, Eduard, Panés, Julián, Salas, Azucena
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2017
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749340/
https://ncbi.nlm.nih.gov/pubmed/27803115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312609
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