Pirfenidone Inhibits Proliferation and Promotes Apoptosis of Hepatocellular Carcinoma Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is the most important cause of cancer-related deaths worldwide. Pirfenidone is an orally available small molecule with therapeutic potential for fibrotic diseases. MATERIAL/METHODS: In this study, we analyzed the effects of different pirfenidone concentrati...

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Bibliographische Detailangaben
Veröffentlicht in:Med Sci Monit
Hauptverfasser: Zou, Wei-Jie, Huang, Zhi, Jiang, Tian-Peng, Shen, Ya-Ping, Zhao, An-Su, Zhou, Shi, Zhang, Shuai
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2017
Schlagworte:
Lab/In Vitro Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749136/
https://ncbi.nlm.nih.gov/pubmed/29276937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.907891
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