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Differential regulations of fibronectin and laminin in Smad2 activation in vascular endothelial cells in response to disturbed flow

BACKGROUND: Atherosclerosis occurs in arterial curvatures and branches, where the flow is disturbed with low and oscillatory shear stress (OSS). The remodeling and alterations of extracellular matrices (ECMs) and their composition is the critical step in atherogenesis. In this study, we investigated...

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Bibliografske podrobnosti
izdano v:J Biomed Sci
Main Authors: Yang, Tung-Lin, Lee, Pei-Ling, Lee, Ding-Yu, Wang, Wei-Li, Wei, Shu-Yi, Lee, Chih-I, Chiu, Jeng-Jiann
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749020/
https://ncbi.nlm.nih.gov/pubmed/29295709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0402-4
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