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Differential regulations of fibronectin and laminin in Smad2 activation in vascular endothelial cells in response to disturbed flow

BACKGROUND: Atherosclerosis occurs in arterial curvatures and branches, where the flow is disturbed with low and oscillatory shear stress (OSS). The remodeling and alterations of extracellular matrices (ECMs) and their composition is the critical step in atherogenesis. In this study, we investigated...

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Publicat a:J Biomed Sci
Autors principals: Yang, Tung-Lin, Lee, Pei-Ling, Lee, Ding-Yu, Wang, Wei-Li, Wei, Shu-Yi, Lee, Chih-I, Chiu, Jeng-Jiann
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749020/
https://ncbi.nlm.nih.gov/pubmed/29295709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0402-4
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